![]() ![]() ![]() Cuffdiff Advanced Options - Sequencher gives you access to all of Cuffdiff's command line options through its innovative GUI.Cuffdiff - Cuffdiff performs the analyses and statistical tests to find significant changes in expression, splicing, and promotor usage.Cuffmerge - You can merge Cufflinks assemblies using Cuffmerge prior to performing Differential Expression analysis.Cufflinks Advanced Options - Sequencher gives you access to all of the Cufflinks command line options through its innovative GUI.Cufflinks - You can now assemble RNA-Seq reads into transcripts from SAM or BAM files using Cufflinks.Cufflinks, Cuffmerge, and Cuffdiff Added to External Data Browser - We have extended the External Data Browser so that you can manage and annotate your RNA-Seq runs.New RNA-Seq Tools Installer - We have created a single downloadable installer to add all the components you need to perform RNA-Seq analysis.RNA-Seq Differential Expression with Cufflinks Suite - You can now perform Differential Expression in Sequencher using Cufflinks.Pricing for Sequencer must be obtained by requesting a quote, which you can do here. It has many new capabilities that can reduce the time required to identify and validate heterozygotes and SNPs in your sequences. ![]() Sequencher capabilities include heterozygote and SNP detection and analysis, cDNA to Genomic DNA large gap alignment, comparative sequencing, support for confidence scores, ORF translation, GenBank feature import, and restriction enzyme mapping. Life Science researchers use Sequencher for many diverse DNA sequence analysis applications including de novo gene sequencing, mutation detection, forensic human identification, systematics, and more. First released almost 15 years ago, Sequencher is currently used for sequence analysis tasks in every major genomic and pharmaceutical company as well as numerous academic and government labs in over 40 countries around the world. It works with all automated sequencers and is widely known for its lightning-fast contig assembly, short learning curve, user-friendly editing tools, and superb technical support. Remember to exit the Sequencher application when you are not actively using it due to limited number of licenses.Sequencher is the industry standard software for DNA sequence analysis.Upon successful installation, Sequencher will automatically connect to the KeyServer, allowing use of the program. To obtain Sequencher for Mac OSX, download and/or run the Sequencher Mac installer.Download the Sequencher Mac license file.Once you have entered the URL, click the “Log On” button, and a message box indicating successful connection to the KeyServer will appear. ![]() During the KeyServer Installation process, you will be prompted to give the “Host DNS name or Address”: Before you will be able to run Sequencher®, you must run the KeyServer Client install files and configure them.
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